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  • Cerebellar stimulation for the treatment of temporal lobe epilepsy.
  • Treatment of Severe Parkinson’s Disease with intraventricular dopamine.
  • Early medical treatment of severe head trauma.
  • Investigation of the Medtronic Synchromed Infusion System for the intrathecal administration of baclofen to treat spasticity.
  • Intrathecal morphine infusion via the SynchroMed Infusion System for treatment of Non-malignant pain.
  • Urinary bladder function in patients with intrathecal baclofen pump.
  • National Acute Brain Injury Study: Hypothermia.
  • A Multicenter, Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Patients with Chronic Non-Malignant Pain.
  • An Open-label, Long-term Safety and Efficacy Study of SNX-111 Administered Intrathecally To Patients Suffering From Chronic Pain Using The Synchromed Infusion System.
  • An Open-Label, Long-Term Safety and Tolerability Study of Ziconotide Administered Intrathecally to Patients with Chronic, Severe Pain.
  • Investigation of the Administration of Lioresal intrathecal (Baclofen Injection) for the Management of Spasticity Associated with Stroke.
  • Use of the InstaTrak During Neurosurgery Procedures.
  • National Acute Brain Injury Study: Hypothermia.
  • A prospective, Non-randomized clinical trial using the ForSite Device to Measure Pupillary Size in outpatient subjects compared to conventional papillary measurements and quantitative papillary dynamics in inpatient subjects where there is potential for early changes in brain volume and subsequent neurologic deterioration.
  • The treatment of medically intractable Trigeminal Autonomic Cephalalgia (TAC) with supraorbital/supratrochlear Nerve Stimulation.
  • Occipital nerve stimulation for treatment of chronic migraine.